http://www.cyto.purdue.edu/cdroms/cyto10a/sponsors/media/dako/mofloxdp/chromosome.pdf WebDec 4, 2014 · The present study highlights the biological effects of chromomycin A2 toward metastatic melanoma cells in culture. Besides chromomycin A2, chromomycin A3 and demethylchromomycin A2 were also identified from the extract derived from Streptomyces sp., recovered from Paracuru Beach, located in the northeast region of Brazil. The …
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WebJan 29, 2024 · CMA3 is an anthraquinone glycosidic antibiotic, produced by Streptomyces griseus ( 21 ). The anti-cancer effects of CMA3 have been proposed since the 1960s ( 22, 23 ). Side effects of CMA3 in advanced breast cancers have interrupted that use ( 24) but it is widely used for DNA staining ( 25 ). WebChromomycin A3 (CMA3) Protamination state of the spermatozoa determines its chromatin integrity status. The lesser the protamine content, the poorer the DNA packaging and the higher the sperm DNA damage. CMA3 binds to the sperm DNA deficient of protamine and stains light yellow [74]. The intensity of color is high in sperm with increased prot ... biochemistry courses columbia sc
Differential Interactions of the Mg2+ Complexes of Chromomycin A3 …
WebChromomycin A3 445 575 CyTRAK Orange™* 457,488,549 615 Ethidium Bromide 493 620 Propidium iodide (PI) 305,540 620 325,360,488 DRAQ5™ 646 681,697 DRAQ7™ 599, 644 678,697 Single dye F ora singl efu c t dy, hx w vp electromagnetic energy to an electron in that molecule (1). The electron moves to an excitation state at the next energy level ... WebApr 27, 2024 · Chromomycin A3 (which is interesting also an antibiotic!), which binds to GC-rich regions of DNA. A Hoechst stain (e.g. 33258 or 33342), that binds to AT-rich regions. Using these DNA stains, we can separate the larger chromosomes from the smaller ones as they will contain more DNA and will thus yield a greater fluorescence signal. WebChromomycin A3, is used as a G-C specific DNA ligand which inhibits transcription and acts as a DNA binding dye. Chromomycin A3 antagonizes enhanced DNA binding of … dagger and flowers tattoo